US Patent 5,476,995
- CLAIM 1. A female transgenic sheep whose somatic and germ cells contain a transgene construct, said transgene construct comprising: (a) a DNA sequence encoding a polypeptide which does not naturally occur in the milk of a non-transgenic sheep; and (b) a .beta.-lactoglobulin promoter operably linked to said DNA sequence encoding said polypeptide; wherein said transgene construct is integrated in such a way that said DNA sequence encoding said polypeptide is expressed in the mammary gland of said sheep to produce a proteinaceous compound comprising said polypeptide in the milk of said female transgenic sheep.